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TECHNOLOGY EVOLUTION

A continuous journey. A brighter tomorrow.

From organ-specific cells to iPSCs: an overview of different cell technologies and their research context.

TECHNOLOGY-REFERENCE MILESTONES

FOUR MILESTONES. A STRONGER TOMORROW.

Cell therapy has evolved significantly over the past decades, from organ-specific cells to induced pluripotent stem cells (iPSCs). Each milestone has expanded our understanding of biology and opened new possibilities for research and clinical application.

The 2000–2015 dates are technology-reference milestones, not Swiss Stem Cell founding or adoption dates, and not dates of first scientific discovery.

  1. 20001st Generation

    Organ CellOrgan-specific cells

    Cells from specific organs or tissues, studied in relation to tissue-specific functions.

    • Tissue-specific characteristics
    • Limited differentiation
    • Historical research context
  2. 20072nd Generation

    Mesenchymal Stromal Cells(MSCs)

    A heterogeneous group of cells studied for differentiation and signalling properties.

    • Multipotent populations
    • Immunomodulatory research
    • Product-specific clinical evidence
  3. 20103rd Generation

    Embryonic Stem Cells(ESCs)

    Pluripotent cells derived from early embryos, with the capacity to form many specialised cell types.

    • Pluripotent
    • Three germ layers
    • Ethical and immune considerations
  4. 20154th Generation

    Induced Pluripotent Stem Cells(iPSCs)

    Adult cells reprogrammed to a pluripotent state, opening possibilities for disease modelling and research.

    • Pluripotent
    • Ectoderm, mesoderm and endoderm
    • Differentiation requires controlled methods

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