MSC – Mesenchymal Stem Cells
Less than a decade after the introduction of organ cells, stem cells and its potential in cell therapy started to appear. The first of its kind is Mesenchymal Stem Cells. It was well known too as a complementary biological treatment which was successfully adopted to alleviate symptoms of early ageing and certain degenerative diseases, and also applied to reduce overall inflammation in many illnesses.
Mesenchymal stem cells are multipotent adult stem cells that are present in multiple tissues, including umbilical cord, bone marrow and fat tissue. Mesenchymal stem cells can self-renew by dividing and can differentiate into multiple tissues including bone, cartilage, muscle and fat cells, and connective tissue. However, being multi-potent, their ability limits its differentiation to only a few cell types, hence, the limitation the restore and regenerate many cell types in body systems.
MSCs are adult stem cells traditionally found in the bone marrow. However, mesenchymal stem cells can also be isolated from other tissues including cord blood, peripheral blood, fallopian tube, and fetal liver and lung.
Upon harvesting, the cells undergo a rigorous and complex series of processes, from high tech filtration under stringent conditions, to cryogenic activity and lyophilisation** to preserve the biological composition and integrity of the cells. The lyophilised** cells then can be securely transported around the world and reactivated again through reconstitution (where the lyophilised cells are hydrated with sterilised water).
** The Lyophilisation of MSCs factors to date is an exclusive and patented preservation technology. This advanced standard of technology has successfully allowed cell therapy to be stable and readily available, superseding older techniques such as ‘Fresh Frozen’, which is temperature sensitive, risking the integrity of cells.